Wisconsin Discovery Portal

Researcher: Timothy Donohue

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Areas of Expertise
  • Bacteria
  • Microbiology
  • Microorganisms
  • Classification
  • Pathways and networks cells use to generate biomass or biofuels from sunlight or other renewable sources of energy
  • Metabolic and regulatory pathways of the photosynthetic bacterium rhodobacter sphaeroides
  • Genome sequencing, microarrays, proteomics, and molecular techniques
  • Biofuels
  • Energy conserving pathways
  • Computational models to help design microbial machines with increased capacity to utilize solar energy
Web Site Timothy Donohue's Department of Bacteriology Website
Curriculum Vitae (CV)
Issued Patent(s)
  • 8,003,390 - Responses to singlet oxygen, issued August 2011.
  • 6,242,244 - Microbial system for formaldehyde sensing and remediation, issued June 2001.
  • 5837481 - Microbial system for formaldehyde sensing and remediation, issued November 1998.
  • 5,747,328 - Microbial system for formaldehyde sensing and remediation, issued May 1998.
  • 5,834,300 - Microbial system for formaldehyde sensing and remediation, issued November 1998.
USPTO Published Applications
  • 20150376659 - Enzymes for producing non-straight-chain fatty acids, published December 2015.
  • 20110171496 - Light-powered microbial fuel cells, published July 2011.
  • 20100299781 - Responses to singlet oxygen, published November 2010.
  • 20080213632 - Light-powered microbial fuel cells, published September 2008.
Recent Publication(s)
  • Structural and Biochemical Characterization of the Early and Late Enzymes in the Lignin β-aryl Ether Cleavage Pathway from Sphingobium sp SYK-6. Pereira JH, Heins RA, Gall DL, McAndrew RP, Deng K, Holland KC, Donohue TJ, Noguera DR, Simmons BA, Sale KL, Ralph J, Adams PD. J Biol Chem. 2016 Mar 3. pii: jbc.M115.700427. [Epub ahead of print]

  • Different Functions of Phylogenetically Distinct Bacterial Complex I Isozymes. Spero MA, Brickner JR, Mollet JT, Pisithkul T, Amador-Noguez D, Donohue TJ. J Bacteriol. 2016 Feb 1. pii: JB.01025-15. [Epub ahead of print]

  • Structural Basis of Stereospecificity in the Bacterial Enzymatic Cleavage of β-Aryl Ether Bonds in Lignin. Helmich KE, Pereira JH, Gall DL, Heins RA, McAndrew RP, Bingman C, Deng K, Holland KC, Noguera DR, Simmons BA, Sale KL, Ralph J, Donohue TJ, Adams PD, Phillips GN Jr. J Biol Chem. 2016 Mar 4;291(10):5234-46. doi: 10.1074/jbc.M115.694307. Epub 2015 Dec 4.

  • A Cardiolipin-Deficient Mutant of Rhodobacter sphaeroides Has an Altered Cell Shape and Is Impaired in Biofilm Formation. Lin TY, Santos TM, Kontur WS, Donohue TJ, Weibel DB. J Bacteriol. 2015 Nov;197(21):3446-55. doi: 10.1128/JB.00420-15. Epub 2015 Aug 17.

View Timothy Donohue's publications at PubMed.
Recent Artistic Works
  • Intra-University: Program Cellular & Molecular Biology, Chemical & Biological Engineering, Civil & Environmental Engineering, BACTER Institute
Research Tools
Research Facilities The United States Department of Energy Great Lakes Bioenergy Research Center, Wisconsin Energy Institute
E-mail Address [email protected]
Phone Number 608-262-4663
Current University UW–Madison
Department Bacteriology
Title Professor
Other Appointments
Director, NIGMS - Biotechnology pre-doctoral training program http://www.bact.wisc.edu/BTP/index.html
Director, DOE – Great Lakes Bioenergy Research Center http://www.greatlakesbioenergy.org/
Address Line 1 5166 Wisconsin Energy Institute
Address Line 2 1552 University Avenue
City Madison
State WI
Zip Code 53726
Bachelor's Degree B.S., Polytechnic Institute of Brooklyn, 1975
Master's Degree M.S., Pennsylvania State University, 1977
PhD Ph.D., Pennsylvania State University, 1980
Other Degrees
Technologies Available for Licensing Singlet Oxygen-Resistant Technologies