Wisconsin Discovery Portal

Researcher: Robert Landick

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Areas of Expertise
  • Cellular regulation
  • Molecular genetics
  • Protein structure
  • Hormone action
  • Cell biology
  • RNA polymerase structure/function
  • Regulation of transcript elongation in bacteria and humans
  • Regulation of bacterial RNAP
  • Regulation of human RNA polymerase II
  • Study of transcriptional regulation in vivo
Web Site Robert Landick's Department of Biochemistry Website
Curriculum Vitae (CV)
Issued Patent(s)
  • 7,595,147 - Methods to identify agents that bind the flap-tip helix of RNA polymerase, issued September 2009.
USPTO Published Applications
  • 20150313221 - Antimicrobial ferulic acid derivatives and uses thereof, published November 2015.
  • 20080193921 - Methods to identify agents that bind the flap-tip helix of RNA polymerase¬†, published August 2008.
  • 20060014197 - In vivo screening methods for identifying inhibitors of RNA polymerases, published January 2006.
  • 20030003481 - Methods to identify agents that bind the flap-tip helix of RNA polymerase, published January 2003.
Recent Publication(s)
  • Mechanisms of Bacterial Transcription Termination: All Good Things Must End. Ray-Soni A, Bellecourt MJ, Landick R. Annu Rev Biochem. 2016 Mar 17. [Epub ahead of print]

  • A Two-Way Street: Regulatory Interplay between RNA Polymerase and Nascent RNA Structure. Zhang J, Landick R. Trends Biochem Sci. 2016 Jan 25. pii: S0968-0004(15)00259-5. doi: 10.1016/j.tibs.2015.12.009. [Epub ahead of print] Review.

  • Mechanism of imidazolium ionic liquids toxicity in Saccharomyces cerevisiae and rational engineering of a tolerant, xylose-fermenting strain. Dickinson Q, Bottoms S, Hinchman L, McIlwain S, Li S, Myers CL, Boone C, Coon JJ, Hebert A, Sato TK, Landick R, Piotrowski JS. Microb Cell Fact. 2016 Jan 20;15(1):17. doi: 10.1186/s12934-016-0417-7.

  • P1 Ref Endonuclease: A Molecular Mechanism for Phage-Enhanced Antibiotic Lethality. Ronayne EA, Wan YC, Boudreau BA, Landick R, Cox MM. PLoS Genet. 2016 Jan 14;12(1):e1005797. doi: 10.1371/journal.pgen.1005797. eCollection 2016 Jan.

View Robert Landick's publications at PubMed.
Recent Artistic Works
Research Tools
Research Facilities
E-mail Address [email protected]
Phone Number 608-265-8475
Current University UW–Madison
Department Bacteriology / Biochemistry
Title Professor
Other Appointments Honorary Associate/Fellow
Address Line 1 5441 Microbial Sciencies Building
Address Line 2 1550 Linden Drive
City Madison
State WI
Zip Code 53706
Bachelor's Degree B.A., University of Michigan
Master's Degree
PhD Ph.D., University of Michigan
Other Degrees
Technologies Available for Licensing RNAPtag Plasmids for Construction of Tagged RNA Polymerase Strains

Tagged RNA Polymerases and Method for Producing Them