Wisconsin Discovery Portal

Researcher: Ann Palmenberg

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Areas of Expertise
  • Cellular regulation
  • Molecular genetics
  • Protein structure
  • Hormone action
  • Cell biology
  • Molecular biology of RNA picornaviruses
  • Protein translation
  • Proteolytic processing
  • RNA synthesis
  • Viral pathogenesis
  • Viral vaccines
  • Vaccine vectors
  • Computer-based sequence analysis
  • Proteolytic agents involved in the viral protein cleavage cascade
  • Designs and tests anti-protease and anti-viral agents
  • Engineers expression and isolation of non-structural proteins for enzymology and crystallography
  • Mechanism of viral RNA replication
  • Computer methods for analyzing viral sequences, predicting the folding of large viral RNA genomes, and visualizing virus surfaces
Web Site Ann Palmenberg's Department of Biochemistry Website
Curriculum Vitae (CV)
Issued Patent(s)
  • 7,947,493 - Compositions and methods for regulating mRNA transcription and translation, issued May 2011.
  • 5,912,167 - Autocatalytic cleavage site and use thereof in a protein expression vector, issued June 1999.
USPTO Published Applications
  • 20100233677 - Full genome sequences of human rhinovirus strains, published September 2010.
  • 20050019808 - Compositions and methods for regulating mRNA transcription and translation, published January 2005.
Recent Publication(s)
  • Cardiovirus Leader proteins bind exportins: Implications for virus replication and nucleocytoplasmic trafficking inhibition. Ciomperlik JJ, Basta HA,¬†Palmenberg AC. Virology. 2016 Jan;487:19-26. doi: 10.1016/j.virol.2015.10.001. Epub 2015 Oct 19.

  • Three cardiovirus Leader proteins equivalently inhibit four different nucleocytoplasmic trafficking pathways. Ciomperlik JJ, Basta HA,¬†Palmenberg AC. Virology. 2015 Oct;484:194-202. doi: 10.1016/j.virol.2015.06.004. Epub 2015 Jun 23.

  • Cadherin-related family member 3, a childhood asthma susceptibility gene product, mediates rhinovirus C binding and replication. Bochkov YA, Watters K, Ashraf S, Griggs TF, Devries MK, Jackson DJ,Palmenberg AC, Gern JE. Proc Natl Acad Sci U S A. 2015 Apr 28;112(17):5485-90. doi: 10.1073/pnas.1421178112. Epub 2015 Apr 6.

  • Production, purification, and capsid stability of rhinovirus C types. Griggs TF, Bochkov YA, Nakagome K,¬†Palmenberg AC, Gern JE. J Virol Methods. 2015 Jun 1;217:18-23. doi: 10.1016/j.jviromet.2015.02.019. Epub 2015 Feb 24.

View Ann Palmenberg's publications at PubMed.
Recent Artistic Works
Research Tools
Research Facilities Robert M Bock Laboratories
E-mail Address [email protected]
Phone Number 608-262-7519
Current University UW–Madison
Department Biochemistry
Title Professor
Other Appointments
Address Line 1 527B Bock Laboratories
Address Line 2 1525 Linden Drive
City Madison
State WI
Zip Code 53706
Bachelor's Degree B.S., St. Lawrence University
Master's Degree
PhD Ph.D., UW–Madison
Other Degrees
Technologies Available for Licensing Protein Inhibitor of Ran Activity

Polyclonal Antibodies Against Cardiovirus 2A, 2B, 2C, 3C, 3A, 3B and 3AB Proteins

Polyclonal Antibodies Against Equine Rhinitis A Virus 3AB, 3C and 3D Proteins

Monoclonal Antibodies That Recognize Recombinant Mengovirus 3C Proteinase

Monoclonal and Polyclonal Antibodies Raised to Recombinant Mengovirus 3D Polymerase