Wisconsin Discovery Portal

Researcher: Michael Sussman

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Areas of Expertise
  • Cellular regulation
  • Molecular genetics
  • Protein structure
  • Hormone action
  • Cell biology
  • Signal transduction in eukaryotes
  • Development of genomic technologies
  • Plasma membrane receptors and ion transporters
  • Arabidopsis thaliana
  • Identifying the in situ functions of hormone receptors and important ion transporters
  • Signaling events that are initiated at the plasma membrane of higher plants
  • Isolates knockout genes
  • Perception and transduction of chemical signals at the plasma membrane of eukaryotes
Web Site Michael Sussman's Department of Biochemistry Website
Curriculum Vitae (CV)
Issued Patent(s)
  • 9,206,473 - Methods for rapid production of double-stranded target dna, issued December 2015.
  • 8,030,477 - Methods for the synthesis of arrays of dna probes, issued October 2011.
  • 7,820,412 - Method of error reduction in nucleic acid populations, issued October 2010.
  • 7,303,872 - Method of error reduction in nucleic acid populations, issued December 2007.
  • 6,375,903 - Method and apparatus for synthesis of arrays of dna probes, issued April 2002.
USPTO Published Applications
  • 20150284767 - Methods for rapid production of double-stranded target dna, published October 2015.
  • 20100281580 - Use of a gene encoding a histidine protein kinase to create drought resistant plants, published November 2010.
  • 20100227780 - Methods for the synthesis of arrays of dna probes, published September 2010.
  • 20100056382 - Dna millichip, published March 2010.
  • 20100016178 - Methods for rapid production of target double-stranded dna sequences, published January 2010.
Recent Publication(s)
  • Mass spectrometric-based selected reaction monitoring of protein phosphorylation during symbiotic signaling in the model legume, medicago truncatula. Van Ness LK, Jayaraman D, Maeda J, Barrett-Wilt GA, Sussman MR, Ané JM. PLoS One. 2016 May 20;11(5):e0155460. doi: 10.1371/journal.pone.0155460. eCollection 2016.

  • Rapid oligo-galacturonide induced changes in protein phosphorylation in arabidopsis. Kohorn BD, Hoon D, Minkoff BB, Sussman MR, Kohorn SL. Mol Cell Proteomics. 2016 Apr;15(4):1351-9. doi: 10.1074/mcp.M115.055368. Epub 2016 Jan 25.

  • Photolithographic synthesis of high-density dna and rna arrays on flexible, transparent, and easily subdivided plastic substrates. Holden MT, Carter MC, Wu CH, Wolfer J, Codner E, Sussman MR, Lynn DM, Smith LM. Anal Chem. 2015 Nov 17;87(22):11420-8. doi: 10.1021/acs.analchem.5b02893. Epub 2015 Nov 5.

  • Regulation of the plasma membrane proton pump (h(+)-atpase) by phosphorylation. Haruta M, Gray WM, Sussman MR. Curr Opin Plant Biol. 2015 Dec;28:68-75. doi: 10.1016/j.pbi.2015.09.005. Epub 2015 Oct 24. Review.


View Michael Sussman's publications at PubMed.
Recent Artistic Works
Collaboration
  • Professor Franco Cerrina, Director of the Center for Nanotechnology and a member of the Department of Computer and Electrical Engineering
Research Tools
  • Maskless DNA array synthesizer which allows one to make a microscope slide containing 786,000 different oligonucleotides in 2 hours
Research Facilities
E-mail Address [email protected]
Phone Number 608-262-8608
Current University UW–Madison
Department Biochemistry
Title Professor
Other Appointments Academic Program Director
Address Line 1 1132B Genetics-Biotechnology Center Building
Address Line 2 425 Henry Mall
City Madison
State WI
Zip Code 53706
Bachelor's Degree B.S., Bucknell University, Biology, 1971
Master's Degree
PhD Ph.D., Michigan State University, Plant Biochemistry, 1976
Other Degrees
Technologies Available for Licensing Method of Error Reduction in Nucleic Acid Populations

A Saturating Population of Insertionally Mutagenized Arabidopsis thaliana Plants

DNA Synthesis with Error Reduction

Faster, Cheaper DNA Synthesis