Wisconsin Discovery Portal

Researcher: Marvin Wickens

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Areas of Expertise
  • Molecular genetics
  • RNA and RNA-protein interactions
  • How mRNAs are regulated
  • How mRNA controls work during development
  • Developmental biology
  • Development and the brain
  • RNA circuitry
  • RNA protein complexes
  • Molecular genetics of C. elegans and Xenopus
Web Site Marvin Wickens' Department of Biochemistry Website
Curriculum Vitae (CV)
Issued Patent(s)
  • 9,249,175 - RNA monomers containing o-acetal levulinyl ester groups and their use in RNA microarrays, issued February 2016.
  • 6,303,311 - Tethered function assay for protein function, issued October 2001.
  • 5,985,575 - Tethered function assay for protein function, issued November 1999.
  • 5,750,667 - System to detect protein-RNA interactions, issued May 1998.
  • 5,726,059 - Prosthetic RNA and use thereof to modify RNA expression, issued March 1998.
USPTO Published Applications
  • 20160145666 - Poly(UG) polymerase, constructs, and methods of making and using the same, published May 2016.
  • 20160138012 - RNA tagging, published May 2016.
  • 20120178638 - RNA monomers containing o-acetal levulinyl ester groups and their use in RNA microarrays, published July 2012.
  • 20040235001 - Regulatory poly(A) polymerase and uses thereof, published November 2004.
Recent Publication(s)
  • The PUF binding landscape in metazoan germ cells. Prasad A, Porter DF, Kroll-Conner PL, Mohanty I, Ryan AR, Crittenden SL,Wickens M, Kimble J. RNA. 2016 Jul;22(7):1026-43. doi: 10.1261/rna.055871.116. Epub 2016 May 10.

  • Pgl germ granule assembly protein is a base-specific, single-stranded RNase. Aoki ST, Kershner AM, Bingman CA,¬†Wickens M, Kimble J. Proc Natl Acad Sci U S A. 2016 Feb 2;113(5):1279-84. doi: 10.1073/pnas.1524400113. Epub 2016 Jan 19.

  • Target selection by natural and redesigned puf proteins. Porter DF, Koh YY, VanVeller B, Raines RT,¬†Wickens M. Proc Natl Acad Sci U S A. 2015 Dec 29;112(52):15868-73. doi: 10.1073/pnas.1508501112. Epub 2015 Dec 14.

  • Protein-RNA networks revealed through covalent RNA marks. Lapointe CP, Wilinski D, Saunders HA,¬†Wickens M. Nat Methods. 2015 Dec;12(12):1163-70. doi: 10.1038/nmeth.3651. Epub 2015 Nov 2.

View Marvin Wickens' publications at PubMed.
Recent Artistic Works
  • University of Washington-Seattle
Research Tools
Research Facilities
E-mail Address [email protected]
Phone Number 608-262-8007
Current University UW–Madison
Department Biochemistry
Title Professor
Other Appointments
Address Line 1 315B DeLuca Biochemistry Laboratories
Address Line 2 433 Babcock Drive
City Madison
State WI
Zip Code 53706
Bachelor's Degree B.A., University of California-Berkeley
Master's Degree
PhD Ph.D., Stanford University
Other Degrees
Technologies Available for Licensing Strain and Vector for Use with the Three Hybrid System

Poly(UG) Polymerase: A Useful New RNA Tool