Wisconsin Discovery Portal

Researcher: Sandro Mecozzi

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Areas of Expertise
  • Analytical chemistry
  • Chemical biology
  • Inorganic chemistry
  • Materials chemistry
  • Organic chemistry
  • Physical chemistry
  • Non-covalent interactions
  • Application of the resulting findings to biochemical and biomedical problems
  • Fluorous phase by synthesizing
  • Self-assembling fluorinated amphiphilic molecules bearing water solubilizing groups and variously fluorinated functionalities
  • Enzymes and their inhibitors
  • Energetics of specific intermolecular interactions
  • Minimal RNA sequences able to bind small organic molecules with high selectivity and affinity
Web Site Sandro Mecozzi's Department of Chemistry Website
Curriculum Vitae (CV)
Issued Patent(s)
  • 9,000,048 - Fluoropolymer-based emulsions for the intravenous delivery of fluorinated volatile anesthetics, issued April 2015.
  • 8,900,562 - Semi-fluorinated block copolymers for delivery of therapeutic agents, issued December 2014.
USPTO Published Applications
  • 20080234389 - Fluoropolymer-based emulsions for the intravenous delivery of fluorinated volatile anesthetics, published September 2008.
  • 20080194500 - Semi-fluorinated block copolymers for delivery of therapeutic agents, published August 2008.
  • 20050214379 - Encapsulation of chemical compounds in fluorous-core and fluorous-inner-shell micelles formed from semifluorinated-block or fluorinated-block copolymers, published September 2005.
Recent Publication(s)
  • Lipid-free fluoropolymer-based propofol emulsions and lipid reversal of propofol anesthesia in rats. Parks CL, Tucker W, Amlong CA, Mecozzi S, Pearce RA. Anesthesiology. 2016 Jun;124(6):1328-37. doi: 10.1097/ALN.0000000000001080.

  • Synthesis, emulsification and self-assembly properties of sugar-containing semifluorinated amphiphiles. Razgulin AV, Mecozzi S. Carbohydr Res. 2015 Apr 10;406:10-8. doi: 10.1016/j.carres.2014.12.009. Epub 2015 Jan 14.

  • Synthesis and characterization of perfluoro-tert-butyl semifluorinated amphiphilic polymers and their potential application in hydrophobic drug delivery. Decato S, Bemis T, Madsen E, Mecozzi S. Polym Chem. 2014 Nov 21;5(22):6461-6471.

  • Base-induced instability of fluorotelomer alcohols. Tucker WB, Mecozzi S. J Fluor Chem. 2013 Dec 1;156. doi: 10.1016/j.jfluchem.2013.08.010.

View Sandro Mecozzi's publications here.
Recent Artistic Works
Research Tools
Research Facilities
E-mail Address [email protected]
Phone Number 608-262-7810
Current University UW–Madison
Department Chemistry / Pharmacy
Title Associate Professor
Other Appointments
Address Line 1 7113 Rennebohm Hall
Address Line 2 777 Highland Avenue
City Madison
State WI
Zip Code 53705
Bachelor's Degree B.S., University of Rome, 1988
Master's Degree M.S., University of Rome
PhD Ph.D., California Institute of Technology, 1996
Other Degrees
Technologies Available for Licensing Improved Micellar Delivery System for Hydrophobic or Fluorophilic Drugs