Wisconsin Discovery Portal

Researcher: John Yin

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Areas of Expertise
  • Applied mathematics
  • Bioscience and engineering
  • Colloids/particle technology
  • Kinetics and catalysis
  • Materials
  • Nanoscale science and engineering
  • Polymers and rheology
  • Process systems engineering
  • Reactor modeling and reaction engineering
  • Thermodynamics
  • Transport phenomena
  • Systems biology
  • Virus-host interactions
  • Systems chemistry
  • Molecular replicators
  • Computational methods to better understand how viruses grow
  • Human rhinovirus
Web Site John Yin's Department of Chemical and Biological Engineering Website
Curriculum Vitae (CV)
Issued Patent(s)
  • 9,206,396 - Methods and devices for quantitative viral assays, issued December 2015.
  • 8,945,486 - Microwell device, issued February 2015.
USPTO Published Applications
  • 20140255276 - Microwell Device, published September¬†2011.
  • 20070111296 - Methods and devices for quantitative viral assays, published May 2007.
Recent Publication(s)
  • Robust kinetics of an rna virus: transcription rates are set by genome levels. Timm C, Gupta A, Yin J. Biotechnology and Bioengineering. 2015 May 20;112(8):1655-1662. doi: 10.1002/bit.25578.

  • Genome rearrangement affects RNA virus adaptability on prostate cancer cells. Pesko K, Voigt EA, Swick A, Morley VJ, Timm C, Yin J, Turner PE. Front Genet. 2015 Apr 1;6:121. doi: 10.3389/fgene.2015.00121. eCollection 2015.

  • Robust kinetics of an RNA virus: Transcription rates are set by genome levels. Timm C, Gupta A, Yin J. Biotechnol Bioeng. 2015 Aug;112(8):1655-62. doi: 10.1002/bit.25578. Epub 2015 May 20.

  • Visualizing infection spread: dual-color fluorescent reporting of virus-host interactions. Swick A, Baltes A, Yin J. Biotechnol Bioeng. 2014 Jun;111(6):1200-9. doi: 10.1002/bit.25170. Epub 2013 Dec 28.
Recent Artistic Works
  • Intra-University Collaboration: Biomedical Engineering, Biomedical Engineering Center for Translational Research, Virology Program, Cancer Biology, Bacteriology
  • Harvard Medical School, Microbiology and Molecular Genetics
  • The Salk Institute for Biological Studies
Research Tools
  • Fluorescence Microscopy
  • Digital Imaging
  • Computer Simulations and Models
  • VSV Growth
  • Bacteriophage T7 Growth
  • Primany Duck Hepatocytes
  • DYNETICA: a computational tool for studying dynamic networks, developed by the Yin Group
Research Facilities
  • UW Carbone Cancer Center
E-mail Address [email protected]
Phone Number 608-316-4323
Current University UW–Madison
Department Chemical and Biological Engineering
Title Professor
Other Appointments
Affiliate Professor, Biomedical Engineering
Faculty Trainer, Biotechnology Training Program, Computation and Informatics in Biology and Medicine (CIBM), Microbiology Doctoral Training Program
Faculty, Graduate Program in Cellular and Molecular Biology, Madison Virology Program
Address Line 1 3172 Discovery Building
Address Line 2 330 North Orchard Street
City Madison
State WI
Zip Code 53715
Bachelor's Degree B.A., Columbia College, Liberal Arts BS, Columbia University, Chemical Engineering
Master's Degree
PhD Ph.D., University of California-Berkeley, Chemical Engineering
Other Degrees Postdoc Fellowship, Max-Planck-Institute fuer Biophysikalishe Chemie (Germany), Biochemical Kinetics
Technologies Available for Licensing Quantitative Comet Assay for Measuring Viral Growth and Resistance to Anti-Viral Compounds

Microwell Moat Prevents Spillover