Wisconsin Discovery Portal

Researcher: Denise Ney

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Areas of Expertise
  • Nutritional genomics
  • Iron metabolism
  • Proteins
  • Obesity and diabetes
  • Dietary fat
  • Energy balance
  • Nutritional management of phenylketonuria (PKU) and gastrointestinal physiology
  • Use of foods made with the whey protein glycomacropeptide (GMP) in the nutritional management of PKU
  • Intestinal adaptation in controlled feeding systems
  • Total parenteral nutrition (TPN)
  • Short bowel syndrome
  • Mechanisms of nutrient-hormone interactions during intestinal adaptation with an emphasis on glucagon like peptide-2 (GLP-2) and insulin-like growth factor-I (IGF-I)
Web Site Denise Ney's Department of Nutritional Sciences Website
Curriculum Vitae (CV)
Issued Patent(s)
  • 9,180,168 - Use of glycomacropeptide to improve women's health, issued November 2015.
  • 8,604,168 - Glycomacropeptide medical foods for nutritional management of phenylketonuria and other metabolic disorders, issued December 2013.
USPTO Published Applications
  • 20160022770 - Use of glycomacropeptide to improve women's health, published January 2016.
  • 20140248414 - Glycomacropeptide medical foods for nutritional management of phenylketonuria and other metabolic disorders, published September 2014.
  • 20130196905 - Use of glycomacropeptide to improve women's health, published August 2013.
  • 20130196024 - Glycomacropeptide medical foods for nutritional management of phenylketonuria and other metabolic disorders, published August 2013.
  • 20100317597 - Glycomacropeptide medical foods for nutritional management of phenylketonuria and other metabolic disorders, published December 2010.
Recent Publication(s)
  • Glycomacropeptide for nutritional management of phenylketonuria: A randomized, controlled, crossover trial. Ney DM, Stroup BM, Clayton MK, Murali SG, Rice GM, Rohr F, Levy HL. Am J Clin Nutr. 2016 Aug;104(2):334-45. doi: 10.3945/ajcn.116.135293. Epub 2016 Jul 13.

  • Clinical relevance of the discrepancy in phenylalanine concentrations analyzed using tandem mass spectrometry compared with ion-exchange chromatography in phenylketonuria. Stroup BM, Held PK, Williams P, Clayton MK, Murali SG, Rice GM, Ney DM. Mol Genet Metab Rep. 2016 Jan 16;6:21-6. doi: 10.1016/j.ymgmr.2016.01.001. eCollection 2016 Mar.

  • Glycomacropeptide is a prebiotic that reduces desulfovibrio bacteria, increases cecal short-chain fatty acids, and is anti-inflammatory in mice. Sawin EA, De Wolfe TJ, Aktas B, Stroup BM, Murali SG, Steele JL, Ney DM. Am J Physiol Gastrointest Liver Physiol. 2015 Oct 1;309(7):G590-601. doi: 10.1152/ajpgi.00211.2015. Epub 2015 Aug 6.

  • Animal models of gastrointestinal and liver diseases. animal models of infant short bowel syndrome: Translational relevance and challenges. Sangild PT, Ney DM, Sigalet DL, Vegge A, Burrin D. Am J Physiol Gastrointest Liver Physiol. 2014 Dec 15;307(12):G1147-68. doi: 10.1152/ajpgi.00088.2014. Epub 2014 Oct 23. Review.
Recent Artistic Works
Collaboration
  • Intra-University Collaboration: Medicine, Discovery to Product (D2P) Advisory Board
  • University of California-Davis, Anatomy, Physiology and Cell Biology
  • Medical College of Wisconsin, Medicine
  • University of Copenhagen, Nutrition, Exercise and Sports
  • Rigshospitalet, Paediatrics and Adolescent Medicine
Research Tools
Research Facilities
E-mail Address [email protected]
Phone Number 608-262-4386
Current University UW–Madison
Department Nutritional Sciences
Title Professor
Other Appointments
Address Line 1 277 Nutritional Sciences
Address Line 2 1415 Linden Drive
City Madison
State WI
Zip Code 53706
Bachelor's Degree B.S., University of California-Davis, 1975
Master's Degree M.S., University of California-Davis and San Diego, 1982
PhD Ph.D., University of California-Davis, 1986
Other Degrees R.D., Registered Dietitian
Technologies Available for Licensing Glycomacropeptide (GMP)-Based Food for the Treatment of PKU and Other Metabolic Disorders

GMP Protein Burns Fat, Boosts Bone Strength in Women