Wisconsin Discovery Portal

Researcher: Wei Xu

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Areas of Expertise
  • Human tumors
  • Prevention
  • Diagnosis
  • Prognosis
  • Epstein-Barr viurs
  • Kaposi's Sarcoma-associated Herpes Virus
  • Human cytomegalovirus
  • Human papillomaviruses
  • Hepatitis B virus
  • Hepatitis C virus
  • Cancer
  • Leukemia
  • Stem cells
  • Intrinsic or acquired tamoxifen resistance in endocrine therapy
  • Histone arginine methylation
  • Epigenetic control of cancer cells
  • Arginine methyltransferase CARM1/PRMT4 protein
  • Role and regulation of histone R methylation in the transcriptional control of ER
  • Mice genetics in tumor prevention
  • Epigenome in breast cancer
Web Site Wei Xu's McArdle Laboratory Website
Curriculum Vitae (CV)
Issued Patent(s)
  • 9,093,940 - Methods of determining initial position of a rotor and systems thereof, issued July 2015.
USPTO Published Applications
  • 20140225548 - Methods of determining initial position of a rotor and systems thereof, published August 2014.
Recent Publication(s)
  • O-GlcNAcylation of co-activator-associated arginine methyltransferase 1 regulates its protein substrate specificity. Charoensuksai P, Kuhn P, Wang L, Sherer N, Xu W. Biochem J. 2015 Mar 15;466(3):587-99. doi: 10.1042/BJ20141072.

  • Prognostic significance of full-length estrogen receptor beta expression in stage I-III triple negative breast cancer. Shanle EK, Onitilo AA, Huang W, Kim K, Zang C, Engel JM, Xu W, Wisinski KB. Am J Transl Res. 2015 Jul 15;7(7):1246-59. eCollection 2015.

  • Correction: differential CARM1 isoform expression in subcellular compartments and among malignant and benign breast tumors. Shlensky D, Mirrielees JA, Zhao Z, Wang L, Mahajan A, Yu M, Sherer NM, Wilke LG, Xu W. PLoS One. 2015 Jun 25;10(6):e0131955. doi: 10.1371/journal.pone.0131955. eCollection 2015.

  • MED12 methylation by CARM1 sensitizes human breast cancer cells to chemotherapy drugs. Wang L, Zeng H, Wang Q, Zhao Z, Boyer TG, Bian X, Xu W. Sci Adv. 2015 Oct 9;1(9):e1500463. doi: 10.1126/sciadv.1500463. eCollection 2015 Oct.

View Wei Xu's publications at PubMed.
Recent Artistic Works
Research Tools
Research Facilities McArdle Laboratory for Cancer Research
E-mail Address [email protected]
Phone Number 608-265-5540
Current University UW–Madison
Department Oncology
Title Associate Professor
Other Appointments
Address Line 1 421A McArdle Cancer Research Building
Address Line 2 1400 University Avenue
City Madison
State WI
Zip Code 53706
Bachelor's Degree B.S., Beijing University, Chemistry, 1991
Master's Degree M.S., Institute of Biophysics, Beijine, 1994
PhD Ph.D., University of Iowa, Biochemistry, 1999
Other Degrees
Technologies Available for Licensing Polyclonal Antibodies to CARM1