Researcher: Michael Gould

Areas of Research Expertise
  • Human tumors
  • Prevention
  • Diagnosis
  • Prognosis
  • Epstein-Barr Viurs
  • Kaposi's Sarcoma-associated Herpes Virus
  • Human Cytomegalovirus
  • Human Papillomaviruses
  • Hepatitis B virus
  • Hepatitis C virus
  • Cancer
  • Leukemia
  • Stem cells
  • Molecular biology of mammary carcinogenesis
  • Breast cancer genetics
  • Oncogenes, Ras signaling
  • Breast cancer chemoprevention and therapy
Web Site Michael Gould's McArdle Laboratory Website
Curriculum Vitae (CV)
Current/Active Funding
  • WARF, 1998-2020, Laboratory share of royalty & licensing income - professor michael n. gould
Issued Patent(s)
  • 7,897,834 - Mutation in the rat adenomatous polyposis coli gene within the human mutation hotspot region, issued March  2011.
  • 7,858,303 - Method of analyzing breast cancer susceptibility and resistance, issued December  2010.
  • 7,056,491 - Monoterpenes and sesquiterpenes as chemotherapeutic and radiation sensitizers and immunomodulators, issued June 2006.
  • 5,846,739 - Immunohistochemical detection assay for carcinoma proliferative status, issued December  1998.
  • 5,773,290 - Mammary gland-specific promoters, issued June 1998.
USPTO Published Applications
  • 20070143867 - Mutation in the rat Adenomatous Polyposis Coli gene within the human mutation hotspot region, published June 2007.
  • 20070056052 - Methods of generating knock-out rodents, published March  2007.
  • 20060240454 - Method of analyzing breast cancer susceptibility and resistance, published October 2006.
  • 20030150001 - Methods of generating knock-out rodents, published August 2003.
Recent Publication(s)
  • Analysis of immune cells from human mammary ductal epithelium reveals Vδ2+ T cells that efficiently target breast carcinoma cells in the presence of bisphosphonate. Zumwalde NA, Haag JD, Sharma D, Mirrielees JA, Wilke LG, Gould MN, Gumperz JE. Cancer Prev Res (Phila). 2016 Jan 25. pii: canprevres.0370.2015. [Epub ahead of print]

  • EBSeq: an empirical Bayes hierarchical model for inference in RNA-seq experiments. Leng N, Dawson JA, Thomson JA, Ruotti V, Rissman AI, Smits BM, Haag JD,Gould MN, Stewart RM, Kendziorski C. Bioinformatics. 2013 Apr 15;29(8):1035-43. doi: 10.1093/bioinformatics/btt087. Epub 2013 Feb 21. Erratum in: Bioinformatics. 2013 Aug 15;29(16):2073.

  • Mcs5c: a mammary carcinoma susceptibility locus located in a gene desert that associates with tenascin C expression. Veillet AL, Haag JD, Remfert JL, Meilahn AL, Samuelson DJ, Gould MN. Cancer Prev Res (Phila). 2011 Jan;4(1):97-106. doi: 10.1158/1940-6207.CAPR-10-0187.

  • The gene desert mammary carcinoma susceptibility locus Mcs1a regulates Nr2f1 modifying mammary epithelial cell differentiation and proliferation. Smits BM, Haag JD, Rissman AI, Sharma D, Tran A, Schoenborn AA, Baird RC, Peiffer DS, Leinweber DQ, Muelbl MJ, Meilahn AL, Eichelberg MR, Leng N, Kendziorski C, John MC, Powers PA, Alexander CM, Gould MN. PLoS Genet. 2013 Jun;9(6):e1003549. doi: 10.1371/journal.pgen.1003549. Epub 2013 Jun 13.


View Michael Gould's publications at PubMed.
Recent Artistic Works
Collaboration
  • Lineberger Comprehensive Cancer Center, University of North Carolina at Chapel Hill
Research Tools
Research Facilities
E-mail Address [email protected]
Phone Number 608-263-6615
Current University UW–Madison
Department Oncology
Title Professor
Other Appointments
Address Line 1 506C McArdle Cancer Research Building
Address Line 2 1400 University Avenue
City Madison
State WI
Zip Code 53706
Bachelor's Degree B.S., UW–Madison, Zoology, 1969
Master's Degree M.S., UW–Madison, Radiological Sciences, 1973
PhD Ph.D., UW–Madison, Radiological Sciences, 1977
Other Degrees
Technologies Available for Licensing Antibodies to NGAL for Detection of Cancer and Kidney Damage

A Mutation in the Rat Adenomatous Polyposis Coli Gene within the Human Mutation Hotspot Region